Mr. ASIWE NICHOLAS
Publication Title Dental occlusion pattern among the Ika speaking people in Delta State, Nigeria
Publication Type Published Research
Publisher International Journal of Current Research
Publication Authors Ese Anibor, Chukwuedu Ojebor, Charity Inikoro and Nicholas Asiwe
Year Published 2021-09-30
Abstract Background: Dental occlusion is the connection between the masticatory surfaces of the maxillary
and mandibular teeth. The occlusion types include the edge to edge bite, the moderate overbite, the
extreme overbite, and the negative overbite. This study offers important information for exploit in
orthodontics, anthropology and forensic science. Objectives: To investigate the pattern of tooth
occlusion among the Ika people, to investigate if there is a significant gender difference, and to
provide a baseline data on the dental occlusion pattern for the Ika ethnic group. Methods: Data was
gotten from 384 subjects fromIka Kingdoms in Delta State, Nigeria (Agbor, Owa-Ekie and Owa-
Alero). Data was collected via observation as subjects were asked to bite, swallow saliva, occlude and
open their mouths, while the association between the upper maxillary and lower mandibular teeth was
observed and recorded. Record of occlusion pattern was taken as mild overbite, edge to edge bite,
negative bite or severe overbite. The Chi-square test was used for inferential statistics and P value less
than 0.05 was considered to be statistically significant. Results:The mild overbite occlusion pattern
had the highest frequency (Males 43.2%, females 42.3%). The negative overbite had the lowest
frequency (Males 2.1%, females 1.0%). There was no significant association between sex and type of
occlusion pattern (p=0.84), and between age and type of occlusion pattern (p>0.05). The second most
common type of occlusion pattern in the age group range of 15-19 years was the severe overbite
occlusion pattern (28%), but in the other age groups (20-24years, 25-30 years) it wasthe edge to edge
bite occlusion pattern,28.2% and 32.8% respectively. Conclusion: The mild overbite occlusion
pattern is the most prevalent type found among the Ika people, and there is no significant association
between sex or age group and type of occlusion pattern.
Publication Title The Effect of High Dietary Salt Consumption on Renal Function in Streptozotocin-Induced Diabetic Male Wistar Rats
Publication Type Published Research
Publisher International Journal of Nutrition Sciences
Paper Link https://ijns.sums.ac.ir/article_48052.html
Publication Authors Asiwe JN, Asiwe N, and Onuh JE
Year Published 2021-10-20
Abstract Background: Salt consumption has been linked to increased risk
of development of type 2 diabetes mellitus and hypertension due to
its glucose resistance and body weight promoting effects. This study
investigated the effect of high dietary salt intake on renal function in
diabetic male Wistar rats.
Methods: Animals were divided into 4 groups (n=7). Group 1 (control
group) were fed with normal rat chow, group 2 (Diabetic) were received
streptozotocin (STZ, 60 mg/kg), group 3 (high Salt) were given 8% salt
diet, and group 4 had both STZ (60 mg/kg) and feeding with 8% salt
diet. Fasting blood glucose was measured weekly and after 28 days prior
to sacrifice, blood pressure measurements and 24 h urine samples were
collected. After sacrifice, blood was collected and serum was separated
for biochemical analysis. The kidneys were removed and preserved in
10% formalin for histological examination.
Results: Serum urea, creatinine and urine urea increased significantly
(p<0.05) across group, when compared with control, while urine creatinine
reduced (p<0.05) in all groups. There was a significant (p<0.05) increase
in superoxide dismutase and catalase in high salt and salt/diabetes groups,
when compared with diabetic group. Glutathione peroxidase significantly
increased (p<0.05) across groups. Histologically, kidneys showed signs
of inflammation in diabetic group, hemorrhagic lesions in high salt group
and both hemorrhagic lesions and inflammation in salt/diabetes group.
Conclusion: High dietary salt consumption was shown to affect tubular
and glomerular functions by altering kidney histoarchitecture and
antioxidant defense system.
Publication Title Awareness of COVID-19 and its Vaccine Acceptability among Young Adult Population of Agbor, Delta State, Nigeria.
Publication Type Published Research
Publisher International Journal of Pharmaceutical and Phytopharmacological Research (eIJPPR)
Publication Authors Asiwe N, Asiwe JN, Asiwe TN, Asiwe PC
Year Published 2022-04-01
Abstract There have been controversies hovering around Coronavirus disease 2019 (COVID-19). Although this disease has claimed lives, the effort is on top gear to stop or prevent the consequences of this virus infection by producing a potent antidote in the form of a vaccine. Many vaccines have been produced and distributed worldwide, yet, the awareness and willingness to accept the vaccine has become a great challenge in many countries, including Nigeria. However, this study evaluates the knowledge, awareness of COVID-19 and willingness to accept the vaccine among the young adult population of Agbor, Delta State, Nigeria. A descriptive, cross-sectional, and multistage sampling technique was adopted in this study. The questionnaire was administered to 184 consented participants who were within the targeted age range. Data obtained were subjected to inferential statistics using the chi-square test, and P<0.05 was considered statistically significant. 106 female and 78 male respondents were interviewed. 78.3% of the female population showed that COVID-19 and its vaccine exist, 17% and 19.2% of respective gender neither convey that it exists or not. The respondents (male and female) agree that there is a vaccine, and 85.8% of the females and 85.9% of the males were not eager to be vaccinated. This study revealed that most respondents believe COVID-19 and its vaccine exist but don't know much about their actions. As a result, many are unwilling to accept the vaccine. Though this finding is not gender-based, more awareness programs should be done to increase the vaccine acceptance rate.
Publication Title Dryopteris dilatata leaf extract ameliorates streptozotocin-induced diabetic nephropathy in male Wistar rats.
Publication Type Published Research
Publisher Nutrire,
Publication Authors Asiwe, J. N., Moke, E. G., Asiwe, N., Yovwin, G. D., Nwogueze, B. C., & Daubry, T. M. E.
Year Published 2022-12-28
Abstract Background
Diabetic nephropathy (DN) is a serious consequence of diabetes mellitus (DM), and it is linked to higher morbidity and mortality in diabetic patients. The quest for cheap therapeutic strategy with lesser side effects remains a major health concern. However, Dryopteris dilatata is a commonly found flavonoid-rich plant with plethora of therapeutic potentials. This study investigated the effect of methanol extract of D. dilatata (MEDd) on streptozotocin-induced diabetic nephropathy in male Wistar rat.
Methods
Animals were randomly selected into five groups (n?=?5) and were treated as follows; group 1 received distilled water (10 mL/kg), group 2 received only STZ (60 mg/kg), groups 3 and 4 received STZ then 400 and 800 mg/kg of MEDd, respectively, while group 5 received STZ then pioglitazone (10 mg/kg). Following 14 days of treatment, animals were euthanized, and blood as well as pancreas and kidney tissues were collected for further studies.
Results
Our results revealed that MEDd significantly reduced STZ-induced hyperglycemia in diabetic rats. Markers of oxidative injury (MDA, nitrite, and GSH) were also significantly ameliorated in the pancreas and kidney of the diabetic rats following treatment with MEDd.
However, renal function markers (creatinine and urea) were significantly attenuated with marked decreased in organ weight in the diabetic rats after treatment with MEDd. Also, serum insulin and corticosterone levels were restored following MEDd treatment.
Conclusion
Methanol extract of D. dilatata demonstrated anti-diabetogenic and reno-protective potential by enhancing in vivo reno-pancreatic antioxidant defense system.
Publication Title knowledge, Attitude and Perception of Women to Cesarean Section in south-eastern Nigeria,
Publication Type Published Research
Publisher Delta State Dental and health journal
Publication Authors Asiwe N., Irozulike F.C., Chigeru P., Buseni V.O., Alorye E.G
Year Published 2023-03-01
Abstract Objective: The study aimed to evaluate the knowledge, attitude and perception of women to cesarean
section (CS) in south-eastern Nigeria.
Materials and Methods: A total of one hundred and eighty-four women from Rivers, Imo, Anambra, Delta
and Bayelsa States were involved in the study. The study adopted a descriptive cross-sectional study design
and a questionnaire was used to collect the data. The females who are Igbos, Urhobos, Isokos, Ikwerres,
Itsekiris and Ijaws were sampled using cluster sampling technique. The data obtained were subjected to
statistical analysis by the use of the Statistical Package for the Social Sciences (SPSS), version 26.
Results: Results showed that the knowledge of cesarean section by the respondents was such that 74.5% of
the total populace understand it as a cut opening of the woman, 17.4% understand it as an assisted delivery
due to laziness to push during labour and 4.3% had no idea on it. The reason for choosing CS was clarified and
the majority of the respondents choose CS due to prolonged labour, 23.4% due to poor dilation of the pelvis,
8.2% gave otherwise reason and 4.9% choose CS to maintain their body physique. Precisely 78.8% of the
study populace see CS as a proper way of delivery and 62% are willing to undergo CS if the need arises.
However 47.8% feel CS is costly, 34.3% are scared of dying, 3.8 are petrified of being stigmatized in the
society and 14.7% think it is not God's wish
Conclusion: The women delved in south-eastern Nigeria have a high level of knowledge on cesarean section.
Nonetheless these women still possesses a minimal level of negative attitude and unwillingness to accept CS.
Publication Title Assessment of Determinants for Choosing Medical Sciences as a Career Path amongst Medical Students of University of Port-Harcourt, Nigeria.
Publication Type Published Research
Publisher Journal of Complementary and Alternative Medical Research
Publication Authors Adheke, O. M., Asiwe, N., Uahomo, P. O., Ezerioha, C. E., Wariboko, L. I., Irozulike, F. C., & Opara, A. I.
Year Published 2023-06-03
Abstract Background and Aim: Presently, medical students form a vital group of aspiring health professionals that are trained in order to assist in promoting healthcare worldwide. However, there is need to understand how these students derive motivation based on various determinants that enable them in choosing to study related disciplines in medical sciences – hence the aim of this present study.
Materials and Methods: Using a qualitative, survey research design, this cross-sectional study comprising of two hundred (200) pre-medical and medical students (98 males and 102 females) between the ages of 16 to 25 years were randomly selected from the University of Port Harcourt and issued a semi-structured questionnaire containing two sections: socio-demographic variables and the determinants influencing career choice in medical sciences.
Results: The majority of respondents in the age range of 16 – 19 years (accounting for a combined 88.0% of student population) did fill their study questionnaires. There were significant age and gender differences in some of the determinants such as parental and peer influence, prospects of travelling abroad to practice, and financial benefits.
Conclusion: The study resolved that there was a need to educate these students to have the right motivation towards aspiring to study in the medical sciences.
Publication Title Does ABO Blood Type Implicate Susceptibility to Respiratory Abnormalities? A Controlled Cross-sectional Study among Indigenous University Students in Rivers State, Nigeria
Publication Type Published Research
Publisher Journal of Complementary and Alternative Medical Research
Publication Authors Asiwe, J.N., Umoren, E. B., Kolawole T.A., Etim K.B., Agbeluyi, A. A., Asiwe N., and Igbokwe, V.
Year Published 2023-07-15
Abstract Background: The blood typing is a genetically defined immune system characteristic that has a well-known role in transplantation and chemotherapy. However, it is unclear what role it could serve in diagnosing or predicting respiratory pathologies. The study aims at investigating the prevalence of respiratory disorder among ABO blood type. This study investigated the prevalence of respiratory disorder among ABO blood types.
Methods: Using a quantitative survey research design, this cross-sectional study comprises of 102 young University students (64 females and 36 males) within the age of 17-28 years, extracted from different local Government Area in Rivers State. A semi-structured questionnaire was used to gather the social demograpgic characteristics of respondent’s. Anthropometric investigations and respiratory function test was done.
Results: The prevalent blood types A, B, O, and AB was 19.6%, 16.7%, 56.9%, and 6.9% respectively. BMI showed that 2.9%, 39.2%, 38.2% and 19.6% was underweight, normal weight, overweight and obese respectively. Respiratory problems were distributed unevenly among blood types, with risk of obstructive pulmonary dysfunction having the highest frequency of occurrence.
Conclusion: The susceptibility to respiratory abnormalities is not associated with any blood type, the risk of obstructive pulmonary disease is higher in blood type O, which is largely influenced by the predominancy.
Publication Title Health Assessment of the Ikwerres and Okrikas Ethnic Group of Rivers State, Nigeria: Using Body Mass Index and Waist-to-Hip Ratio
Publication Type Published Research
Publisher Journal of Complementary and Alternative Medical Research
Publication Authors 22. Asiwe, N., Irozulike, F. C., Wariboko, L. I., & Adheke, O. M
Year Published 2023-07-31
Abstract Background: Body mass index (BMI), and waist-to-hip ratio (WHR), are acceptable indicators in
accessing health status that are used to assess cardiometabolic disorders and to predict future
health risks. The aim of the study assesses the health status of Ikwerres and Okrikas ethnic groups
using BMI and WHR. Methods: The study adopted a descriptive cross-sectional study design where it comprises of 300
respondents (139 females and 161 males) between the age of 18-37 years were randomly
selected. BMI was deduced from the division of body weight by the square root of standing height
and WHR by direct division of waist circumference and hip circumference.
Results: A study of 300 subjects from Ikwerre and Okrika ethnic groups in Rivers State found that
11.8% were underweight, 76.4% normal weight, 7.5% overweight, and 4.3% obese in males. The
association of BMI was significant with gender differences, and the waist-to-hip ratio showed that
69.6% of males were within the normal range. BMI and waist-to-hip ratio are significant.
Conclusion: BMI shows gender differences and the association between BMI and WHR is
significant.
Publication Title Prevalence of Dysmenorrhea and its Management among Undergraduate Students of the University of Port Harcourt, Nigeria
Publication Type Published Research
Publisher Asian Journal of Advanced Research and Reports
Publication Authors Irozulike F.C., Asiwe, N., Ekokodje, J.W., Wedeh, M.S., Izibeya, J.D., and Filima., P.L
Year Published 2023-11-06
Abstract Background: Dysmenorrhea is a pain felt by women before or during menstruation and is
accompanied by some symptoms like headache, dizziness, food cravings, mood swings, and
fatigue. Many ways have been adopted for the management of dysmenorrhea. The study aims to
evaluate the prevalence of dysmenorrhea and its management among university students. Methods: A total of two hundred (200) female university students were involved in this study.
A cross-sectional descriptive study design was used where students were sampled randomly
a questionnaire was used to collect data and data obtained were analyzed using IBM SPSS
version 26.
Results: The study found that a majority of the population experiences dysmenorrhea during
menstruation (81.5%) and the majority of respondents experienced menstrual flow within 4-5 days
with 37% experiencing severe pain. Symptoms include anxiety, mood swings, tender breasts, food
cravings, fatigue, irritating mood, depression, dizziness, vomiting, diarrhea, and headache.
Management of dysmenorrhea varies, with 23.5% using synthetic drugs and 1.5% using local and
herbal practices.
Conclusion: There was a high prevalence of dysmenorrhea among the University students and
presenting symptoms like mood swings, fatigue, and diarrhea, with most using local/herbal
medication.
Publication Title Pattern of Earlobe Attachment among Igbo Ethnic Group of Nigeria,
Publication Type Published Research
Publisher Asian Journal of Advanced Research and Reports
Publication Authors Asiwe N., Irozulike, F.C., Filima P.L., Wedeh, M. S., and Yirate, B. N.,
Year Published 2023-11-04
Abstract Background: The earlobe is the fleshy lower region of the outer ear that lacks cartilage and is
firmly attached to the side of the face. Every individual either has an attached or unattached pattern
of earlobe attachments. The study aims to evaluate the prevalence pattern of earlobe attachment
among the Igbo ethnic group of Nigeria.
Methods: 384 respondents (192 males and 192 females) were involved in the study and adopted
an observational research design where multi-stage random sampling was used. A questionnaire
was administered and retrieved. The data obtained were analyzed using IBM SPSS version 26 and
chi-square was used as inferential statistics.
Results: 57.8% of the male population have an unattached earlobe pattern and 42.2% have
attached earlobe patterns. In comparison, 51.6% of the female population had an attached pattern
of the earlobe, whereas only 48.4% had an unattached pattern of the earlobe. The association
between earlobe pattern and gender revealed no gender difference Conclusion: The unattached pattern of earlobe attachment is predominant among males and an
attached pattern of the earlobe is predominant among females of the Igbo ethnic group of Nigeria.